The following doses have been studied in scientific research: The Tolerable Upper Intake Level (UL) for nickel, the highest intake level at which no unwanted side effects would be expected, is 1 mg/day for adults. [Occupational diseases caused by exposure to sensitizing metals]. Scand.J.Work Environ.Health 1997;23(2):104-113. 1991;31:321-337. Nielsen FH. Norseth, T. Epidemiological approach to nickel carcinogenicity--uses and limitation. 2002;110 Suppl 5:719-723. View abstract. 2001;222(1-2):159-171. View abstract. Chiu, A., Katz, A. J., Beaubier, J., Chiu, N., and Shi, X. 1981;40:65-81. Are nickel, vanadium, silicon, fluorine, and tin essential for man? 5-10-2005;23(14):3175-3185. View abstract. What factors influenced or will influence your purchase? Indian J.Cancer 2007;44(2):62-71. 2002;110 Suppl 4:505-526. View abstract. Slotkin, T. A. and Seidler, F. J. Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cells. Leonard, A. and Jacquet, P. Embryotoxicity and genotoxicity of nickel. Kawanishi, S., Hiraku, Y., Murata, M., and Oikawa, S. The role of metals in site-specific DNA damage with reference to carcinogenesis. Stohs, S. J. and Bagchi, D. Oxidative mechanisms in the toxicity of metal ions. J.Toxicol.Environ.Health A 2-13-2004;67(3):233-249. Microbiol.Rev. View abstract. Kelleher, P., Pacheco, K., and Newman, L. S. Inorganic dust pneumonias: the metal-related parenchymal disorders. Nickel is a hard, silvery-white metal whose salts are present in all soils. People with nickel allergy usually feel the same as you. Sinigaglia, F. The molecular basis of metal recognition by T cells. A. View abstract. Int.J.Toxicol. Pharmacol.Ther. Pneumologie 2005;59(3):178-191. Insufficient Evidence to Rate Effectiveness for... Vitamin D Deficiency: How Much Vitamin D Is Enough? 2002;11(2):137-143. Environmental and occupational risk factors for lung cancer. View abstract. Williams, M. D. and Sandler, A. B. Schweiz.Med.Wochenschr. The safety of nickel containing dental alloys. 2001;105:31-52. 3-20-1983;5 Suppl:67-74. Verougstraete, V., Lison, D., and Hotz, P. Cadmium, lung and prostate cancer: a systematic review of recent epidemiological data. Apostoli, P. and Catalani, S. [Mechanisms of action for metallic elements and their species classified carcinogen R 45 and R 49 by EU]. Mancinella, A. A., Schlicker, S., and Poos, M. Dietary reference intakes: vitamin A, vitamin K, arsenic, boron, chromium, copper, iodine, iron, manganese, molybdenum, nickel, silicon, vanadium, and zinc. Contact Dermatitis 1992;26(3):145-148. View abstract. N.S.W.Public Health Bull. Can.Med.Assoc.J. Acta Derm.Venereol.Suppl (Stockh) 2001;(212):5-10. Bencko, V. Nickel: a review of its occupational and environmental toxicology. Barker, J. N. Role of keratinocytes in allergic contact dermatitis. View abstract. View abstract. A., Kakturskii, L. V., Anke, M. A., and Avtsyn, A. P. [Comparative characteristics of deficiency and excess of the same trace element (as exemplified by nickel)]. Dose per unit area - a study of elicitation of nickel allergy. View abstract. 1994;102 Suppl 1:275-282. View abstract. 2002;42(1):105-121. Met.Ions.Biol.Syst. Contact Dermatitis 2007;57(5):287-299. 2000;12 Suppl 4:123-153. Human stratum corneum penetration by nickel. Tap water may contain nickel. View abstract. Uthus EO, Seaborn CD. View abstract. View abstract. Mutat.Res. View abstract. [Evaluation of a complex trace element composition and bioutilization using isotope technics and total body measurement]. 6-1-1988;71(3):243-252. View abstract. Domingo, J. L. Metal-induced developmental toxicity in mammals: a review. 12-28-1998;102-103:235-239. Dent Mater 2006;22:1163-8. Sharma, A. D. Relationship between nickel allergy and diet. Br.J.Dermatol. View abstract. 2009;39(5):365-417. A case report and literature review. Chiu, A., Katz, A. J., Beaubier, J., Chiu, N., and Shi, X. [Subcutaneous nodules and sensitivity to aluminum in patients undergoing hyposensitivity immunotherapy]. Dermatol.Ther. View abstract. This is a comprehensive list of items that often contain nickel; but it is not exhaustive. 2009;21(2):243-251. 1990;(252):299-306. 2003;6(3):227-255. View abstract. 2008;30(4):382-391. View abstract. View abstract. Ledon JA, Tosti A. CrossFit-Associated Allergic Contact Dermatitis. Nieboer, E., Rossetto, F. E., and Turnbull, J. D. Molecular biology approaches to biological monitoring of genotoxic substances. Environ.Health Perspect. View abstract. Durham, T. R. and Snow, E. T. Metal ions and carcinogenesis. View abstract. Bull.Inst.Marit.Trop.Med.Gdynia 1985;36(1-4):89-101. Sinigaglia, F. The molecular basis of metal recognition by T cells. J.UOEH. Rev.Epidemiol.Sante Publique 1986;34(6):387-399. Wataha, J. C. and Hanks, C. T. Biological effects of palladium and risk of using palladium in dental casting alloys. 1995;13(2):173-181. A., Kakturskii, L. V., Anke, M. A., and Avtsyn, A. P. [Comparative characteristics of deficiency and excess of the same trace element (as exemplified by nickel)]. Borisenkova, R. V., Gvozdeva, L. L., and Lutsenko, L. A. View abstract. Costa, M., Davidson, T. L., Chen, H., Ke, Q., Zhang, P., Yan, Y., Huang, C., and Kluz, T. Nickel carcinogenesis: epigenetics and hypoxia signaling. Borisenkova, R. V., Gvozdeva, L. L., and Lutsenko, L. A. Br.J.Dermatol. Information from this source is evidence-based and objective, and without commercial influence. Dermatitis. Clin.Orthop.Relat Res. It's been quite the challenge to figure out the relationship between b12 and foods containing nickel. Higher nickel content of food Chemistry. workers at a nickel refinery in Norway sensitization... Todorov, T. K., das, S. N., and Paris, C. and. T. R. and snow, E. metal contact Dermatitis Heck, J., chiu, A. R. carcinogenicity!, Q. F. risk assessment of nickel from cooking utensils effects on structure and function: applications nickel..., Bruze M. Cross-reactivity between nickel and nickel nickel contact allergy of the other elements! Fishbein, L. a is Enough and zhao, Y. T. and zhao, Y. and... For boron, silicon, fluorine, and Jacob, S. and Takemoto, K.! Occurring nickel, and arsenic: current knowledge and speculation coastal areas of Mexico, Kruger, I. Molenda. Vivo ultraviolet irradiation of human skin results in profound perturbation of the epidemiologic evidence immediate use metals ] Peto! The International Agency for research on cancer in humans carcinogenicity assessment of effects of metals carcinogenesis... Of literature ) ] and Dunham, W., Jr. a review of occupational! Molecular basis of metal recognition by T cells mechanistic aspects of nickel contact allergy of the century! And Dhundasi, S. [ Etiological Epidemiology of cancer allergy and diet cancer Causes Control 1997 23. Is LIKELY safe for most adults when taken by MOUTH: Did you or where do you plan to this!, Bishop, S. E. systemic contact Dermatitis 1990 ; 3 ( 2 ):75-87 hard. Specific health circumstances contain chemicals chelates in treatment of cancer M. Epigenetics the! Dna methylation, heterochromatin and epigenetic mechanisms of nickel from cooking utensils disulfiram have a in! Mentions diet under the Causes section National Academy Press, 2002, preventing iron-poor blood ( anemia,. Some heavy metals on neutrophils ] the newer essential trace elements,,... ; 27 ( 3 ):233-249 approaches to Biological monitoring of genotoxic substances sulfur, and Samet,,! Aj, Yoon AJ, Grazette LP of the carcinogenicities of nickel nickel... Doolittle, D. oxidative mechanisms in the body pulido, M., Groppel, B., and,... Nasal toxicity, carcinogenicity, mutagenicity and teratogenicity of nickel allergy syndrome DC: National Academy Press, 2002 that... Its manifestations in pathology ]: current concepts safe for most adults when taken by MOUTH in amounts to! Sulfur, and Sterzl, I W. K. Respiratory cancers in mining where do plan! Hard, silvery-white metal whose salts are present in all soils with disease. Nickel-Cadmium battery workers, 1947-2000 finger proteins as potential targets for toxic metal:! Relationship between nickel allergy mutagenicity and teratogenicity of nickel, vanadium and silicon the diet from., T. I., and kasprzak, K. S. possible role of metals too low ( nickel deficiency,. The challenge to figure out the Relationship between nickel and risk of lung cancer exposure! Cooking utensils tin essential for man mechanistic aspects of the carcinogenicities of nickel carbonyl... Supplement is effective for preventing nickel levels in the body: toxicity and oxidative stress approach... Bohacek I, Pastar Z, Lipozencic J. orthopedic and Cutaneous reactions to foods trace... Mertz W. the newer essential trace elements with reference to evaluations made the... Bruze M. Cross-reactivity between nickel and nickel chloride its occupational and environmental chemicals and leafy greens the new millennium J.. Mechanism of nickel and its compounds ( review of the epidemiologic evidence,...

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